TLDR: Anyone else experiencing very high TSH since starting GLP1? How did you fix the slowed digestion/absorption issue?
I’ve been on Levothyroxine for decades - my thyroid was nuked by radiation about 25 years ago - it’s dead.
My thyroid levels were good before starting glp1, but weight just kept piling on and I started having major POTS symptoms as well. Working with my Endo to drop the weight, I started compounded Tirzepitide. I started noticing no weight loss or very very slow weight loss compared to others. I know you’re not supposed to compare your journey to others but I just wasn’t seeing the big changes everyone raved about for months.
Went back to Endo to do bloodwork - I also have very low iron, vitamin D, and have pernicious anemia and need B12 injections daily. Decided to also run thyroid panel to see if levels were on due to some weight loss - I’ve lost about 25 pounds in 8 months. Not complaining by any means, but some folks are seeing that loss in 1-2 months. Thyroid levels came back and T3 and T4 were normal but parathyroid was low and my TSH came back THROUGH THE ROOF. Like on the scale of .5 - 4.5 mine came back at 14! You’d think I’d need less meds due to weight loss, but quite the opposite, my body isn’t absorbing the meds at all. Figured I was taking my protein shakes and iron supplements too close to timing my meds - they have calcium and need 4+ hours between each other. Decided to go a full 1.5 months making sure everything was spaced correctly. New levels just came back and TSH is 11 - so still very off and having major hypo issues. Decided to bump up from .150 of Levi to .175 and see if that does anything. It’s been about 2 weeks and I don’t feel any difference yet and the scale isn’t moving any faster but I know it’s takes a while to kick in.
My fear is, my stomach is never empty anymore after I eat in the evening and when I wake up, I still have food in my stomach to block absorption. Our solution is currently keep going up on meds levels and see if giving my body more meds will help the loss of full absorption.
Anyone else ever dealt with the slow gastric emptying blocking med absorption?
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